NEWS
ApplyPolygenicScore 3.0.1 (2025-03-05)
Added
- Added hemizygous allele handling to dosage calculation
- Added toggle to hexbinplot at sample size threshold in
create.pgs.with.continuous.phenotype.plot
Changed
- Updated INDEL effect switch reporting by strand flip checker
- Updated data structuring for automated statistical analysis in
apply.polygenic.score
ApplyPolygenicScore 3.0.0
Added
- Added handling of overlapping deletion allele notation
- Added secondary PGS/VCF variant matching method using rsID after first attempt with genomic coordinates
- Added checks for rsID as an optional column in input PGS weight files
- Added functionality to assess allele matches and correct strand flips
ApplyPolygenicScore 2.0.0
Changed
- Renamed functions starting with reserved vocabulary for S3 generic methods merge. -> combine.
ApplyPolygenicScore 1.0.0
ApplyPolygenicScore 0.1.0